Research progress in detection methods of phthalates in food
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摘要: 塑化剂即邻苯二甲酸酯类物质是塑料中用以改善塑料可塑性和提高塑料强度的一种常用化学助剂。该化学助剂不以化学键方式与塑料成分结合,在适当条件下不断向周围环境释放而污染食品。有些种类塑化剂毒性较大,长期食用残留有这些塑化剂的食品会对人体健康造成极大危害。本文对食品中塑化剂的来源、危害以及国内外对食品中塑化剂残留检测方法进行了评述及展望,以促进我国对食品质量安全进行更有效的检测和监管。Abstract: Plasticizer-phthalates is a group of important chemical additions to improving plastic and strength of plastic, which in plastic products are not chemically but physically bound to the polymer materials. So they can be dispersed into the environment and contaminating food under appropriate conditions. Some members of the phthalates have severe toxicity and their residues in foods are harmful to the health of human. In this article, the source, harm and common analytical methods for phthalate esters acid residues in foods were reviewed based on references, in order to promote more effective residual detection and supervision.
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Keywords:
- phthalates /
- residue /
- detection /
- review
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[1] 卢跃鹏, 胡筱静, 方慧文, 等.凝胶渗透色谱-气相色谱/质谱法测定塑料桶装食用油中四种邻苯二甲酸酯[J].粮食与油脂, 2010, 11:37-39. [2] Muczynski V, Cravedi J P, Lehraiki A.Effect of mono- (2-ethylhexyl) phthalate on human and mouse fetal testis:In vitro and in vivo approaches[J].Toxicology and Applied Pharmacology, 2012, 261:97-104.
[3] Olsén L, Lind L, Lind P M.Associations between circulating levels of bisphenol A and phthalate metabolites and coronary risk in the elderly[J].Ecotoxicology and Environmental Safety, 2012, 80:179-183.
[4] 李婷, 汤智, 洪武兴.分散固相萃取-气相色谱-质谱法测定含油脂食品中17种邻苯二甲酸酯[J].分析化学, 2012, 40 (3) :391-396. [5] Harris C A, Henttu P, Parker M G, et al.The estrogenie activity of phthalate esters in vitro[J].Environ Health Perspect, 1997, 105 (9) :802-811.
[6] 吴惠勤, 朱志鑫, 黄晓兰, 等.不同类别食品中21种邻苯二甲酸酯的气相色谱-质谱测定及其分布情况研究[J].分析测试学报, 2011, 30 (10) :1079-1087. [7] 杜丹.食品中邻苯二甲酸酯含量检测方法的研究[J].中国卫生产业, 2012, 13:125. [8] 张道来, 林学辉, 周明.气相色谱-质谱法快速测定罗氏海盘车中6种邻苯二甲酸酯类有机污染物[J].岩矿测试, 2012, 31 (1) :159-165. [9] Michele D C, Alessia P, Giampiero S, et al.Determination of phthalate esters in wine using solid-phase extraction and gas chromatography-mass spectrometry[J].Food Chemistry, 2008, 111:771-777.
[10] 中华人民共和国卫生部.关于公布食品中可能违法添加的非食用物质和易滥用的食品添加剂名单 (第六批) 的公告[EB/OL].[2011-06-01].http://www.moh.gov.cn/publicfiles/business/htmlfiles/mohwsjdj/s7891/201106/51902.htm. [11] 佟晓芳.乳制品中邻苯二甲酸酯类化合物残留量检测方法[J].中国乳品工业, 2012, 40 (1) :59-62. [12] 李一尘, 徐静, 董伟峰, 等.气相色谱及气相色谱-质谱法检测食品中增塑剂[J].检验检疫学刊, 2012, 22 (5) :40-44. [13] Self R L, Wu W H.Rapid qualitative analysis of phthalates added to food and nutraceutical products by direct analysis in real time/orbitrap mass spectrometry[J].Food Control, 2012, 25:13-16.
[14] 郑向华, 林立毅, 方恩华, 等.固相萃取-气相色谱-质谱法测定食品中23种邻苯二甲酸酯[J].色谱, 2012, 30 (1) :27-32. [15] Heaven M W, David N.Recent analyses using solid phase microextraction in industries related to food made into or from liquids[J].Food Control, 2012, 27:214-227.
[16] Luo Y B, Yu Q W, Yuan B F, et al.Fast microextraction of phthalate acid esters from beverage, environmental water and perfume samples by magnetic multi-walled carbon nanotubes[J].Talanta, 2012, 90:123-131.
[17] Dévier M H, Menach K L, Viglino L, et al.Ultra-trace analysis of hormones, pharmaceutical substances, alkylphenols and phthalates in two French natural mineral waters[J].Science of the Total Environment, 2013, 443:621-632.
[18] 刘芃岩, 高丽, 申杰, 等.固相微萃取-气相色谱法测定白洋淀水样中的邻苯二甲酸酯类化合物[J].色谱, 2010, 28 (5) :517-520. [19] Guo Y, Kannan K.Challenges encountered in the analysis of phthalate esters in food stuffs and other biological matrices[J].Analytical and Bioanalytical Chemistry, 2012, 404:2539-2554.
[20] 黄永辉.凝胶渗透色谱-气相色谱/质谱法同时测定食用油中22种邻苯二甲酸酯[J].分析科学学报, 2012, 28 (2) :217-221. [21] 柴丽月, 辛志宏, 蔡晶, 等.食品中邻苯二甲酸酯类增塑剂含量的测定[J].食品科学, 2008, 29 (7) :362-365. [22] 徐向华, 方晓明, 丁卓平, 等.高效液相色谱测定牛奶中邻苯二甲酸酯的方法研究[J].化学通报, 2008, 71 (6) :420-424. [23] 陈文锐, 王瑄.毛细管气相色谱法测定进品奶粉中酞酸酯类增塑剂污染情况[J].中国公共卫生, 2000, 16 (7) :636. [24] 王建立, 路平, 杨凯, 等.牛脏器中邻苯二甲酸酯类环境激素分析方法的研究[J].北京农学院学报, 2011, 26 (2) :31-34. [25] 卢春山, 李玮, 屠海云, 等.气相色谱-质谱联用测定食品中的邻苯二甲酸酯[J].分析测试学报, 2010, 29 (10) :1036-1040. [26] Cortazar E, BartoloméL, Delgado A, et al.Optimisation of microwave-assisted extraction for the determination of nonylphenols and phthalate esters in sediment samples and comparison with pressurised solvent extraction[J].Analytica Chimica Acta, 2005, 534:247-254.
[27] Wu X L, Hong H J, Liu X T, et al.Graphene-dispersive solid-phase extraction of phthalate acid esters from environmental water[J].Science of the Total Environment, 2013, 444:224-230.
[28] Cacho J I, Campillo N, Vi觡as P, et al.Determination of alkylphenols and phthalate esters in vegetables and migration studies from their packages by means of stir bar sorptive extraction coupled to gas chromatography-mass spectrometry[J].Journal of Chromatography A, 2012, 1241:21-27. [29] 王鑫, 许小苗, 俞晔, 等.固相萃取气相色谱法同时测定水中的酞酸酯类环境激素[J].食品工业科技, 2008, 29 (4) :287-289. [30] 彭丹祺, 孙同华, 贾金平, 等.活性炭固相微萃取-气相色谱联用测定海水中酞酸酯[J].分析化学研究简报, 2009, 37 (5) :715-717. [31] 高洁, 杨促, 叶长文, 等.基于杯[6]芳烃萃取头的固相微萃取-气相色谱法测定啤酒中痕量的酞酸酯类化合物[J].色谱, 2009, 27 (3) :356-358. [32] Ostrovsk伥I, 覶abala R, Kubinec R, et al.Determination of phthalate sum in fatty food by gas chromatography[J].Food Chemistry, 2011, 124:392-395. [33] Adeniyi A A, Okedeyi O O, Yusuf K A.Flame ionization gas chromatographic determination of phthalate esters in water, surface sediments and fish species in the Ogun river catchments, Ketu, Lagos, Nigeria[J].Environmental Monitoring Assessment, 2011, 172:561-569.
[34] Farajzadeh M A, Mogaddam M R.Air-assisted liquid-liquid microextraction method as a novel microextraction technique;Application in extraction and preconcentration of phthalate esters in aqueous sample followed by gas chromatography-flame ionization detection[J].Analytica Chimica Acta, 2012, 728:31-38.
[35] Farahani H, Ganjali M R, Dinarvand R, et al.Screening method for phthalate esters in water using liquid-phase microextraction based on the solidification of a floating organic microdrop combined with gas chromatography-mass spectrometry[J].Talanta, 2008, 76:718-723.
[36] 王硕, 王琨, 朱华平, 等.气相色谱-质谱法检测食用油中的邻苯二甲酸酯[J].食品研究与开发, 2010, 31 (9) :127-130. [37] Zhang Y F, Lee H K.Low-density solvent-based vortexassisted surfactant-enhanced-emulsification liquid-liquid microextraction combined with gas chromatography-mass spectrometry for the fast determination of phthalate esters in bottled water[J].Journal of Chromatography A, 2013, 1274:28-35.
[38] 李任伟, 程明川, 李想, 等.凝胶渗透色谱-高效液相色谱法检测食用油中邻苯二甲酸酯的含量[J].食品工业科技, 2011, 32 (12) :484-485. [39] Ranjbari E, Hadjmohammadi M R.Magnetic stirring-assisted dispersive liquid-liquid microextraction followed by high performance liquid chromatography for determination of phthalate esters in drinking and environmental water samples[J].Talanta, 2012, 100:447-453.
[40] 张明明, 孙远明, 杨艺超, 等.高效液相色谱法测定食用油中邻苯二甲酸酯类污染物总量[J].中国油脂, 2012, 37 (7) :46-50. [41] 王楠, 王伟, 张玉, 等.瓶装饮料中DNOP、DBP类增塑剂的液相色谱检测方法[J].中国食品学报, 2012, 12 (8) :179-185. [42] 祝伟霞, 杨冀州, 袁萍, 等.大气压化学电离-液相色谱串联质谱法测定油基食品中的18种邻苯二甲酸酯类化合物[J].现代食品科技, 2012, 28 (1) :115-118. [43] 李拥军, 熊文明, 陈坚文, 等.固相萃取/高效液相色谱-串联质谱法测定罗非鱼中9种邻苯二甲酸酯[J].分析测试学报, 2012, 31 (3) :278-283. [44] Zhang M C, Sheng Y L.An indirect competitive fluorescence immunoassay for determination of dicyclohexyl phthalate in water samples[J].Journal of Fluorescence, 2010, 20:1167-1173.
[45] Zhang M C, Cong Y, Sheng Y L, et al.A direct competitive enzyme-linked immunosorbent assay by antibody coated for diethyl phthalate analysis[J].Analytical Biochemistry, 2010, 406:24-28.
[46] Zhang M C, Liu B L, Cong Y, et al.Development of highly specific fluorescence immunoassay and enzyme-linked immunosorbent assay for detection of dimethyl phthalate in water samples[J].Food and Agricultural Immunology, 2011, 22:297-309.
[47] Zhang M C, Hu Y R, Liu S H, et al.Rapid monitoring of dipropyl phthalate in food samples using a chemiluminescent enzyme immunoassay[J].Food Analytical Methods, 2012, 5:1105-1113.
[48] Zhang M C, Liu S H, Zhuang H S, et al.Determination of dimethyl phthalate in environment water samples by a highly sensitive indirect competitive ELISA[J].Applied Biochemistry and Biotechnology, 2012, 166:436-445.
[49] Zhang M C, Wang Y, Yu X N, et al.Rapid monitoring of dicyclohexyl phthalate in foods using the direct competitive ELISA[J].Food and Agricultural Immunology, 2013, DOI: 10.1080/09540105.2013.768964.
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