异淀粉酶改性玉米淀粉胶囊的研制及性能研究

详细信息

Fabrication and character of a new capsule made from modified corn starch treated with isoamylase

Chemical Engineering College, Ocean University of China
Qingdao Technical College
College of Medicine, Guizhou University
Qingdao Institute of Biomass Energy and Bioprocess Technology, Chinese Academy of Sciences

摘要: 以玉米淀粉为主料,聚乙烯醇、海藻酸钠、甘油及卡拉胶等为辅料制备异淀粉酶改性玉米淀粉胶囊,并对其吸湿性、崩解性等进行测定。结果表明:经0.2m L 10mg/m L的异淀粉酶处理5min后得到的玉米淀粉在溶胀、糊化等一系列过程中操作可控性增强,改性后溶胶的粘度降低了约42%。通过添加辅料3.0%卡拉胶、0.2g KCl、1.0%甘油、0.5%海藻酸钠及0.2%聚乙烯醇,所得淀粉植物胶成膜性、阻水性及强度均明显增强,相比于明胶胶囊崩解时限缩短。
- 异淀粉酶 /
- 改性玉米淀粉 /
- 胶囊 /
- 性能
Abstract: A novel plant hard capsule was made from corn starch modified by isoamylase, and polyving akohol, alginate and carrageenan was used as uxiliary materials. Then the new kind of capsule film was tested about its characters of humility sensitivity and disintegration. It was indicated that, the process of starch expansion and gelation could be controlled very well, when the corn starch treated by 0.2m L 10mg/m L isoamylase for 5min.The viscosity of the sol was reduced effectively as well. The film-forming characters and strength of the starch film were enhanced, by added 3.0% carrageenan, 0.2g KCl, 1.0% glycerinum, 0.2% PVA and 0.5% alginate, also, the disintegration time of the capsule would be controlled effectively and reasonably.
- isoamylase /
- modified corn starch /
- capsule /
- fabrication

[1]	Vinod D Vilivalam, Lisbeth lllum, Khurshid lqbal.Starch capsule:an alternative system for oral drug delivery research focus[J].2000, 2 (2) :64-69.
[2]	Bae H, Cha D, Whiteside W, et al.Film and pharmaceutical hard capsule formation properties of mungbean, waterchestnut, and sweet potato starches[J].Food Chem, 2008, 106:96-105.
[3]	张良, 王燕斐, 刘宏生, 等.天然植物高分子药用胶囊的研究与发展[J].高分子学报, 2013 (1) :1-10.
[4]	刘宇, 周传新.木薯淀粉胶的制备工艺及其制得的植物胶、植物胶囊:中国, 101338045[P].2009-01-07.
[5]	康明丽.淀粉酶及其作用方式[J].食品工程, 2008, 3 (9) :11-15.
[6]	郭卫强, 唐鹤生.新型海洋植物硬空心胶囊的研制[J].食品与机械, 2012, 1 (28) :235-237.
[7]	张小菊, 姜发堂.植物硬空心胶囊性能检测[J].化学与生物工程, 2008, 25 (12) :77-78.
[8]	YY/T0188.8药品检验操作规程第8部分制剂通则[S].1995.
[9]	国家药典委员会编.中华人民共和国药典[M].第一版附录72.北京:化学工业出版社, 2005.
[10]	连喜军, 王吰, 刘旭.α-淀粉酶水解马铃薯淀粉制备抗性淀粉[J].粮食与油脂, 2009 (2) :11-15.
[11]	朱香云.异淀粉酶酶解玉米淀粉的性质及其成膜性研究[D].天津:天津大学, 2010.